Why do some songs merely entertain, where others penetrate to the depths of our souls? Why does one song leave us unmoved, where another evokes passion or joy or sorrow?
We might find an answer by framing the question differently:
What is harmony?
Any thoughtful combination of notes can produce a pleasing sound. But not all composition is inspired, not all orchestration sublime. And even then, only once in a long while does the coalescence of notes and instrumental arrangement produce a true symphonic masterpiece, one that carries us to new heights of exultation.
Add to that the poetry of artful lyrics seasoned with shrewd insight into the human condition, and you will experience the fusion of heart and mind in a glorious oneness of divine synchronicity.
There is a single word to describe this.